Aclasta is given as an injection through a needle placed into a vein. You will receive this injection in a clinic or hospital setting. The medicine must be given slowly through an IV infusion, and can take at least 15 minutes to complete. Aclasta is sometimes given only once per year.
Does Aclasta need to be refrigerated?
Instructions for use and handling. Aclasta must not be mixed or given intravenously with any other medication and must be given through a separate vented infusion line at a constant infusion rate. If refrigerated, allow the refrigerated solution to reach room temperature before administration.
Can you drink alcohol after an Aclasta infusion?
Alcohol is known to increase fracture risk by decreasing bone mineral density and promoting osteoporosis. People taking Aclasta should stop drinking alcohol, or at least reduce the amount of alcohol that they drink.
Is zoledronic acid the same as Aclasta?
Aclasta contains the same active ingredient found in Zometa (zoledronic acid), used for oncology indications, and a patient being treated with Zometa should not be treated with Aclasta. Patients must be appropriately hydrated prior to administration of Aclasta.
What is Aclasta infusion used for?
Aclasta is a solution for infusion (drip) into a vein that contains the active substance zoledronic acid. What is Aclasta used for? Aclasta is used to treat osteoporosis (a disease that makes bones fragile) in women who have been through the menopause and in men.
How often should Aclasta be given?
Aclasta (a bisphosphonate) is administered once every 1-2 years via a 15 minute intravenous infusion, and replaces daily or weekly tablets (e.g. Alendronate (Fosamax) or Etidronate) in osteoporosis patients.
How long does Aclasta stay in the body?
A 100mL infusion will last at least 15 minutes. For osteoporosis, each dose of Aclasta lasts one year. Your doctor will check your condition and may prescribe further annual doses.
What are the benefits of Aclasta?
The active substance in Aclasta, zoledronic acid, is a bisphosphonate. It stops the action of the osteoclasts, the cells in the body that are involved in breaking down the bone tissue. This leads to less bone loss in osteoporosis and less disease activity in Paget’s disease.
Is Aclasta a steroid?
Aclasta contains the active substance zoledronic acid. It belongs to a group of medicines called bisphosphonates and is used to treat post-menopausal women and adult men with osteoporosis or osteoporosis caused by treatment with corticosteroids used to treat inflammation, and Paget’s disease of the bone in adults.
Is zoledronic acid a chemo drug?
Zoledronic acid (Zometa) is not cancer chemotherapy, and it will not slow or stop the spread of cancer. However, it can be used to treat bone disease in patients who have cancer. Zoledronic acid is in a class of medications called bisphosphonates.
What is Aclasta injection?
♦ Zoledronic acid (Aclasta) is an. injectable drug indicated for the treatment of osteoporosis in post- menopausal women. It belongs to a class of drugs called bisphosphonates. Zoledronic acid (Aclasta) is given as a once-yearly injection.
How long can you stay on Aclasta?
Aclasta may work for longer than one year, and your doctor will let you know if you need to be treated again. Your doctor may advise you to take calcium and vitamin D supplements (e.g. tablets) for at least the first ten days after being given Aclasta.
How do I take Aclasta?
Aclasta is given as an injection through a needle placed into a vein. You will receive this injection in a clinic or hospital setting. The medicine must be given slowly through an IV infusion, and can take at least 15 minutes to complete. Aclasta is sometimes given only once per year. Follow your doctor’s instructions.
What is the active substance in Aclasta?
What Aclasta contains The active substance is zoledronic acid. Each bottle with 100 ml of solution contains 5 mg zoledronic acid (as monohydrate). One ml solution contains 0.05 mg zoledronic acid (as monohydrate). The other ingredients are mannitol, sodium citrate and water for injections.
How long should Aclasta infusion last?
• Patients, especially elderly patients and those receiving diuretic therapy, should be appropriately hydrated prior to administration of Aclasta. • A single dose of Aclasta should not exceed 5 mg and the duration of infusion should be at least 15 minutes (see section 4.2).
How is Aclasta administered for the treatment of osteoporosis?
For the treatment of post-menopausal osteoporosis, osteoporosis in men and the treatment of osteoporosis associated with long-term systemic glucocorticoid therapy, the recommended dose is a single intravenous infusion of 5 mg Aclasta administered once a year.
