Emodin is an anthraquinone of natural origin (Rheum emodi and many other plants) used in traditional Chinese medicine. It is a plant resin usually obtained from the rhubarb. It has laxative and antiviral effects and it is not devoid of toxicity.
Is emodin anthraquinone?
Emodin, a natural anthraquinone, has shown potential as an effective therapeutic agent in the treatment of many diseases including cancer.
Where is emodin found?
Rhubarb
Emodin is an anthraquinone obtained from traditional herb Rhubarb or Rheum officinale and Polygonum cuspidatum. This has been evaluated for its immunosuppressive and antiinflammatory activities. Therefore, keeping the inflammatory effects in mind, Song et al.
Is emodin poisonous?
Emodin is the main toxic component in Chinese medicinal herbs such as rhubarb.
What is the structure of emodin?
Emodin anthrone
| PubChem CID | 122635 |
|---|---|
| Structure | Find Similar Structures |
| Molecular Formula | C15H12O4 |
| Synonyms | Emodin anthrone Emodinanthrone 491-60-1 1,3,8-Trihydroxy-6-methyl-10H-anthracen-9-one emodin-9-anthrone More… |
| Molecular Weight | 256.25 |
What is emodin good for?
In vitro and in vivo pharmacological studies have revealed that emodin exhibits a variety of pharmacological benefits, including anticancer, antiinflammatory, antivirus, antibacterial, anti‐allergic, anti‐osteoporotic, anti‐diabetic, immunosuppressive, neuroprotective and hepatoprotective effects.
Is emodin an alkaloid?
A total of seventeen phytochemicals including seven alkaloids (piperine, strychnine, brucine, stachydrine, tetrandrine, frangchinoline and sinomenine), four phenols (paeonol, honokiol, magnolol and eugenol) and six anthraquinones (emodin, rhein, chrysorphanol, aloe-emodin, physcion and 1,8-dihydroxyanthraquinone) was …
What is the use of Barbaloin?
Barbaloin have variety of pharmacological activity such as strong inhibitory effect on histamine release, anti-inflammatory, cathartic, antiviral, antimicrobial, anticancer, antioxidant activity and alternative for pharmaceutical or cosmetic applications.
What is the structure of Chrysophanol?
It is a C-3 methyl substituted chrysazin of the trihydroxyanthraquinone family. Chrysophanol (other names; 1,8-dihydroxy-3-methyl-anthraquinone and chrysophanic acid) was found commonly within Chinese medicine and is a naturally occurring anthraquinone.
Where Barbaloin is found?
aloe plant
Barbaloin is C-glucoside of aloe emodin anthrone, found in the outer rind of the aloe plant. It has been reported to constitute up to 30% of the aloe plants dried leaf exudates and play an important part in the defense mechanisms against herbivores.
Emodin is a trihydroxyanthraquinone that is 9,10-anthraquinone which is substituted by hydroxy groups at positions 1, 3, and 8 and by a methyl group at position 6. It is present in the roots and barks of numerous plants (particularly rhubarb and buckthorn), moulds, and lichens.
Does emodin induce apoptosis in hepatocellular carcinoma cells?
Emodin induces apoptotic responses in the human hepatocellular carcinoma cell lines (HCC) Mahlavu, PLC / PRF / 5 and HepG2. The addition of emodin to these three cell lines led to inhibition of growth in a time- and dose-dependent manner.
What is the excretion rate of anthraquinone [14C]emodin?
Absorption, excretion, tissue distribution and metabolism of the anthraquinone [14C]emodin was studied after a single oral administration (approx. 50 mg/kg) to rats. Urinary excretion amounted to 18(+/- 5)% dose in 24 hr and to 22(+/- 6)% in 72 hr.
